肝脏影像的薄板样条弹性配准

Thin plate spline deformable registration of liver images

目的在弹性配准中考虑肝脏周边解剖结构间运动的不连续性。方法采用双薄板样条弹性配准方法,利用制定治疗计划过程中于参考影像中勾画的轮廓线信息对特征点进行分区。结果对临床病例进行配准,沿人体上下方向偏移量绝对值的平均误差从配准前的11.25mm降到配准后的1.80mm,标准方差从2.60mm降到1.39mm。结论该方法考虑了脏器间运动的不同模式,并且不需要在配准中对目标影像进行轮廓线勾画。

Objective To take the discontinuous movements of anatomic structures around liver into account in deformable registration. Methods Bi-TPS （thin plate spline） deformable registration was proposed. The method partitioned the feature points according to the physician＇s segmentation of the template image during treatment planning. Results The average error and the standard deviation （SD） in modeling the absolute value of the displacement in the superior/inferior direction were reduced from （11.25±2.60）mm before registration to （1.80±1.39）mm after registration in a patient with liver tumor. Conclusion The proposed method can take the different motions of anatomic structures into consideration and allow segmented registration without delineating contours in the target images.