重组人表皮生长因子对体表创面愈合的疗效观察

Observation of the curative effect of recombinant human epidermal growth factor(rhEGF)on all kinds of dermal wound

目的:观察重组人表皮生长因子(rhEGF)对各类体表创面的治疗作用。方法:应用重组人表皮生长因子(rhEGF)治疗各种术后创面,观察不同创面的愈合时间、愈合质量、不良反应等指标。结果:共治疗80例,总有效率100%;与对照组相比,普遍愈合时间缩短(P<0.01),创面再生上皮质量较好,瘢痕轻或无;所有病例均无不良反应。结论:在各类体表创面的治疗中应用rhEGF,能缩短愈合时间,提高愈合质量。

Objective To observe the curative effect of recombinant human epidermal growth factor （rhEGF） on all kinds of dermal wound. Methods Apply recombinant human epidermal growth factor （rhEGF） to all kinds of burn wound and dermal wound, then observe the healing time, healing quality, unhealthy reaction. Results In total treated 80 cases patient, total effective rates is 100%; compare with the control group, the healing time is shorter （P〈0.01）, re- epitheliogenic quality of the dermal wound is rather better, there is no scar or s light scar; there is no unhealthy reaction happened in any case. Conclusion Applying the rhEGF to all kinds dermal wound can shorten the healing time, improve the healing quality.