小儿急性呼吸道感染血浆D二聚体变化的研究

Investigation of D Dimer in Blood Plasm in Children with Acute Respiratory Infection

目的了解急性呼吸道感染(AR-TIs)患儿血浆D二聚体水平变化及临床意义。方法对600例住院AR-TIs患儿用奥斯邦生物工程有限公司生产的耐科卡读数仪检测血浆D二聚体水平。结果急性呼吸道感染患儿血浆D二聚体水平明显高于对照组;AR-TIs临床表现与D二聚体水平相关,临床出现喘憋和严重感染患儿血浆D二聚体水平明显升高;白细胞总数升高的AR-TIs患儿血白细胞总数与血浆D二聚体水平呈明显正相关。结论AR-TIs尤其是支气管肺炎患儿体内存在高凝状态,D-二聚体可以作为重症肺炎血液高凝状态的检测指标。对于重症肺炎患儿给与相应的治疗对疾病的转归可能有积极的临床意义。

Objective Find out the level and clinical significance of D dimer in blood plasm in children with acute respiratory infection.Methods The D dimer level of blood plasm in 600 children with acute respiratory infection was detected by NycoCard Reader Ⅱ which was made in AusBio Company. Results The D dimer level in children with acute respiratory infection is much higher than that in control group; The level of D dimer is associated with clinical situation of acute respiratory infection. The level in children with pant or serious infection raised significantly;the total white blood cells and the D dimer level of blood plasm are positive correlation. Conclusion There is a hypercoagulabale state in the children with acute respiratory infection, especially with bronchial pneumonia. D dimmer can be used as a standard that means hypercoagulabale in serious pneumonia. Correspond treatment to the children with serious pnetunonia may have a energetic clinical significance to the turnover.