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男性2型糖尿病合并痛风患者胰岛素敏感性指数变化及意义 被引量:4

Change of Insulin-sensitivity index(ISI) in male diabetes mellitus 2(DM2)with gout and its meaning
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摘要 目的探讨男性2型糖尿病合并痛风患者胰岛素敏感性指数(ISI)的变化,并分析其原因及意义。方法全部病例来自我科门诊及住院患者。对82例2型糖尿病合并痛风患者、79例无痛风的2型糖尿病患者和78例痛风患者进行空腹血糖(FPG)、胰岛素(FINS)、血尿酸(Ua)测定,并计算胰岛素敏感性指数(ISI)。结果2型糖尿病合并痛风患者较无痛风的糖尿病患者具有明显的高胰岛素血症、ISI显著降低(P<0.05)。结论2型糖尿病合并痛风患者具有明显高胰岛素血症和胰岛素抵抗。在糖尿病治疗过程中应引起高度重视。 Objective To investigate the change of insulin-sensitivity index( ISI )in male diabetes meUitus 2(DM2) with gout and analyze its reason and meaning. Methods All data came from patients of our department. For 82 patients with DM2 and gout, 79 patients with DM2 without gout and 78 patients of gout,we detect its FPG,FINS,Insulin,Ua et al,and calculate ISI.Results Patients of DM2 with gout have significantly higher insulin and lower ISI( P 〈 0.05)compared to those DM2 without gout. Conclusion DM2 with gout have significantly higher blood insulin and insulin resistance, should pay more attention to.
出处 《中国实验诊断学》 北大核心 2009年第4期526-527,共2页 Chinese Journal of Laboratory Diagnosis
关键词 痛风 糖尿病 胰岛素抵抗 gout diabetes insulin resistance
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