核素肝胆动态显像对胆囊结石患者胆囊运动功能的研究

STUDY OF GALLBLADDER MOTOR FUNCTION IN PATIENTS WITH GALLSTONES BY RADIONUCLIDE HEPATOBILIARY SCINTIGRAPHY

为了探求胆囊结石患者胆囊运动功能的状况，用(99m)锝一二乙基乙酸苯氨基亚氨二醋酸（(99m)Tc-EHIDA）为肝胆显像剂，以脂肪餐为胆囊收缩刺激剂，通过单光子计算机断层（SPECT）装置及计算机系统定量地研究了12例正常受试者和12例胆囊结石患者的胆囊运动情况。结果表明；潜伏期和排胆期在两组间无显著性差异（P＞0．05），而胆囊结石患者的排胆分数和排胆率明显低于正常对照组（P＜O．01）。说明胆囊结石患者的胆囊运动功能是降低的。

In order to evaluate the gallbladder motor function of patients with gallstones,a study was undertaken to establish hepatobiliary scintigraphy with SPECT device and computer system,using 99mTc-EHIDA as imaging agent and a fatty meal as stimulus to release endogenous cholecystokinin to analyse quantitatively the gallbladder motor function in 12 normal subjects and 12 patients with gallstones. The results showed that the latent period and emptying period did not differ significantly in normal subjects and the patients (P>0. 05),but the gallbladder ejection fraction and emptying rate of the patients were significantly lower than those of the normal subjects (P<0. 01). This suggested that the gallbladder motor function in patients with gallstones was reduced.