摘要
目的:研究消肿止痛胶囊的药效作用。方法:以大鼠肠系膜微循环法、小鼠疼痛扭体法、小鼠耳肿胀法观察消肿止痛胶囊的药效作用。结果:消肿止痛胶囊能改善大鼠肠系膜微循环障碍,减少由醋酸引起的小鼠疼痛反应,显著抑制二甲苯所致小鼠耳肿胀。结论:消肿止痛胶囊具有活血化瘀、消肿止痛作用,可为临床应用提供实验依据。
OBJECTIVE: To study the pharmacodynamics of Xiaozhongzhitong capsules. METHODS: The pharmacodynamics of Xiaozhongzhitong capsules was studied through rat mesenteric microcirculation test, mouse pain writhing test and mouse ear swelling test. RESULTS: The Xiaozhongzhitong capsules improved rats' mesenteric microcirculation disturbance, attenuated the pain action of mouse induced by acetate acid, and significantly inhabited the ear swelling of mouse caused by dimethylbenzene. CONCLUSION: Xiaozhongzhitong capsules showed proved efficacy in activating blood, dissolving stasis, eliminating swelling and alleviating pain, and the results serve as an experimental basis for the clinical application of Xi-aozhongzhitong capsules.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第12期898-899,共2页
China Pharmacy
关键词
消肿止痛胶囊
药效学
消肿止痛
Xiaozhongzhitong capsule
Pharmacodynamics
Eliminating swelling and alleviating pain