摘要
目的:探讨肿节风注射液所致不良反应(ADRs)的一般规律和特点,为临床合理用药提供参考。方法:检索1994~2007年国内医药学期刊报道的肿节风注射液所致ADRs文献,共计25例,并进行统计、分析。结果:肿节风注射液所致ADR在儿童年龄组发生率较高,多在用药过程中前30 min内发生;肿节风注射液ADRs主要表现为变态反应(88.0%),严重者可出现过敏性休克。结论:临床医师、药师应重视肿节风注射液的ADRs,坚持合理用药。
OBJECTIVE: To study the general pattern and characteristics of the adverse drug reactions (ADRs) induced by Zhongjiefeng injection for reference of rational drug use. METHODS: A total of 25 ADRs cases induced by Zhongjiefeng in jection reported in domestic medical journals during 1994--2007 were analyzed statistically. RESULTS: ADRs of Zhongjiefeng injection were more often seen in children and occurred usually within 30 min after injection, appeared mainly as allergic re- actions (88.0%) or anaphylactic shock in severe cases. CONCLUSION: Clinical physicians and pharmacists should stay on high alert to the ADRs induced by Zhongjiefeng injection and adhere to rational drug use.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第12期945-947,共3页
China Pharmacy
关键词
肿节风注射液
药品不良反应
文献分析
Zhongjiefeng injection
Adverse drug reaction
Literature analysis