胎盘血栓形成与不良妊娠结局

Placental thrombosis and poor pregnancy outcome

胎盘是母胎界面维持胎儿在宫内营养和生长发育的重要器官。胎盘血栓形成与不良妊娠结局如反复自然流产、子痫前期和胎儿生长受限等密切相关。遗传性和获得性血栓形成倾向、母体及胎儿胎盘循环等高危因素可导致胎盘血栓形成。临床应重视胎盘血栓形成的诊治及预防。

Placenta located at maternal-fetal interface is a very important organ for fetal nutritional requirement and growth development. Thrombosis in placenta is associated with a spectrum of adverse pregnancy outcomes including recurrent spontaneous abortion, preeclampsia and fetal growth restriction; Some of high risk factors, such as hereditary and acquired thrombophilia, maternal and fetal circulation abnormality, play an important role in the pathogenesis of placental thrombosis. Diagnosis, treatment and prevention about placental thrombosis should be paid much attention in clinical practice.