摘要
目的:探讨全身炎症反应综合征一般治疗时核因子-kB活化及IL-6合成的情况及黄芩苷对他们的影响。方法:用中性粒细胞核因子-kB活性测定法、血清免疫因子IL-6放射免疫浓度测定法测定30例全身炎症反应综合征一般治疗组、30例全身炎症反应综合征加用黄芩苷组及30例正常人组中性粒细胞核因子-kB活性、血清免疫因子IL-6放射免疫浓度。结果:全身炎症反应综合征一般治疗时核因子-kB活化及IL-6合成增加。黄芩苷可抑制他们的变化。结论:黄芩苷是治疗全身炎症反应综合征的有效药物。
Objective : To explore the activation of NF - kB and Synthesise of IL - 6 in systemic inflammatory response syndrome and the effect of Baicalin. Methods : Children were divided into sham group, experiment group and normal group. The changes of the activation of NF - kB and Synthesise of IL - 6 were watched by using especting NF - kB in PMN and radioimmunoassay. Results : The activation of NF - kB and Synthesise of IL - 6 increased obviously in systemic inflammatory response syndrome. Baicalin inhibited their changes. Conclusion: Baicalin is effective in systemic inflammatory response syndrome.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第12期1810-1811,共2页
Liaoning Journal of Traditional Chinese Medicine
基金
广州市科技项目(2006-2008)
关键词
全身炎症反应综合征
核因子-KB
白细胞介素6
Systemic inflammatory response syndrome
Nuclear factor kappa B
Interleukin - 6