摘要
采用皮下注射乙酰苯肼造成小鼠溶血性贫血模型,以生大黄煎剂灌胃制备小鼠血虚模型,观察了哈氏平颏海蛇乙醇提取物对两种贫血模型小鼠红细胞数及血红蛋白含量的影响。结果表明,海蛇提取物能显著提高溶血性贫血模型小鼠红细胞数与血红蛋白含量,对大黄所致血虚模型小鼠血红蛋白含量有升高作用,但对红细胞数无影响。研究结果提示海蛇提取物对溶血性贫血模型小鼠的红细胞有较好的保护作用。
Effects of the extracts from Lapemis hardwickii on RBCs count and Hb content were studied in the both of mice model of which was made by acetylphenyhydrozine (APH) for hemolytic anemia and of by Chinese rubarb for Xue Xu (debility due to blood deficiency). The results showed that counts of red blood cell (RBC) and content of hemoglobin (Hb) of experimental group in hemolytic anemia model mice were higher significatly than that of control gooup in hemoly ticanemia mice. The content of Hb was increased in Xue Xu mice model,but no marked effect on the counts of RBCs. The study showed that the extract could have a better profective effect on red blood cells of hemolytic anemia mice.
出处
《中国海洋药物》
CAS
CSCD
1998年第1期38-40,共3页
Chinese Journal of Marine Drugs
关键词
涨蛇
提取物
贫血
红细胞
血红蛋白
动物模型
Lapemis hardwickii
extract
anemia model
red blood cell
hemoglobin
