摘要
目的应用实时心肌超声造影评价X综合征患者心肌冠脉血流储备。方法选择X综合征患者10例,对照组7例,应用超声造影剂SonoVue进行实时心肌超声造影检查,分别测定静息状态和腺苷负荷后造影剂微泡达到峰值的最大声强度(A),再充盈平均速度(β)及AXB,并测定冠脉血流储备(负荷前后AXB的比值)。结果X综合征患者静息时A与对照组相比差异无统计学意义(P〉0.05),β值和AXD值低于对照组(P〈0.01),X综合征患者冠状动脉血流储备值明显低于对照组,差异有统计学意义(P〈0.01)。结论X综合征患者心肌微血管功能受损,实时心肌超声造影可评价X综合征患者心肌冠脉血流储备。
Objective To evaluate myocardial coronary flow reserve of syndrom X by real-time myocardial contrast echocardiography(MCE). Methods Ten patients with syndrome X and seven normal subjects were involved in the study. Real time MCE was performed with acoustic contrast SonoVue,and the peak video density (A), and re-turgor velocity of microvessel (β), and the product of A × β of quiescent condition and after adenosin loading were detected,and also the coronary flow reserve (CFR, the ratio of A ×β circa-adenosin loading). Results There was no significant difference of A between syndrom X and contrast group in quiescent condition, the β and product of A × β of patients with syndrome X were lower than those of contrast group, the CFR of syndrome X was obviously less than that of contrast group. Conclusions Myocardial microvessel function is abnormal in syndrome X, real-time MCE is useful for evaluate myocardial coronary flow reserve.
出处
《中华超声影像学杂志》
CSCD
北大核心
2009年第4期308-310,共3页
Chinese Journal of Ultrasonography