期刊文献+

前列腺素E_1治疗糖尿病周围神经病变142例疗效分析

下载PDF
导出
摘要 目的评价血管活性药物前列腺素E1(PGE1)治疗糖尿病周围神经病变的有效性和安全性。方法采用自身治疗前后对照的方法,针对142例糖尿病周围神经病变患者应用生理盐水250ml+PGE1静脉滴注,1次/d,15d为1个疗程。结果PGE1治疗后糖尿病周围神经病变的神经症状明显改善,且提高了MCV和(或)SCV的传导速度,且无不良反应。结论前列腺素E1(PGE1)治疗糖尿病周围神经病变安全有效。
作者 王姝文
出处 《中国实用医药》 2009年第11期75-76,共2页 China Practical Medicine
  • 相关文献

参考文献6

  • 1Shimizu H,Shimonura Y,Kurihara A,et al.Immediated improvement of diabetic mononeuropathy after imtravenous administration of prostaglandin E4.Jap J Med,1990,29(2):222-225.
  • 2Tawata M,Nitta K,Kurihara A,er al.Effects of a single drip infusion of lipo-prostaglandin E1 on vibratory to ryhtresh old patients with diabetic neuropathy.Prostaglandins,1995,49(1):27-39.
  • 3Toyota T,Hirata Y,Ikeda Y,et al.Lipo-PGE1,a new lipid encapsulated preparation of prostaglangin E1:placebo and prostaglandin E1 controlled multicentertrials in patients with diabetic neuropathy and leg ulcers.Prostaglandins,1993,46(5):453-468.
  • 4钟玲,吴世和,郭常辉,严钟德.尼莫通治疗糖尿病周围神经病变疗效观察[J].中国糖尿病杂志,1999,7(1):48-49. 被引量:45
  • 5李剑波 陈家伟.糖尿病神经病变的发病机理及现代认识[J].实用糖尿病杂志,1997,5(1):3-3.
  • 6卢爱华,胡敏.前列腺素E_1在糖尿病慢性并发症中的应用研究[J].国外医学(内分泌学分册),2000,20(3):135-137. 被引量:110

二级参考文献14

  • 1方思羽.尼莫地平静脉滴注治疗急性脑梗塞的临床研究[J].内科急危重症杂志,1997,3(2):58-60. 被引量:9
  • 2方思羽,内科急危重症杂志,1997年,3卷,58页
  • 3张蜀平,天津医药,1997年,6卷,337页
  • 4Cawello W,Leonhardt A,Schweer H,etal.Dose proportional pharmacokinetics of alpro-stadil (prostaglandin E1)in healthyvolunteers following intravenous infusion 〔J〕.Br J Clin Pharmacol,1995,40:273~276.
  • 5Anggard E.The biological activities of three metabolites of prostaglandin E1 〔J〕.ActaPhysiol Scand,1996,66:509~510.
  • 6Yasuda H,Maeda K,Sonobe M,et al.Metabolic effect of PGE1 analogue O1206.αCD onnerve Na+-K+-ATPase activity of rats with streptozotocin-induced diabetes is mediatedvia cAMP: possible role of cAMP in diabetic neuropathy 〔J〕.Prostaglandins,1994,47:367~378.
  • 7Okada S,Ichiki K,Tanokuchi S,et al.Effect of prostaglandin E1 on therenin-aldosterone system in patients with diabetic nephropathy 〔J〕.J Int MedRes,1993,21:126~132.
  • 8Young MJ, Veves A,Smith JV, et al.Restoring lower limb blood flow improvesconduction velocity in diabetic patients 〔J〕.Diabetologia,1995,38:1051~1054.
  • 9Partanen J,Niskanen L,Lehtinen J,et al.Natural history of peripheral neuropathy inpatients with non-insulin-dependent diabetes mellitus 〔J〕. N Engl J Med,1995,333:89~94.
  • 10Yasuda H,Sonobe M,Hatanaka I,et al.A new prostaglandin E1 analogue (TFC-612)prevents a decrease in motor conduction velocity in streptozocin-diabetic rats 〔J〕.BiochemBiophys Res Commun,1998,150:225~230.

共引文献158

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部