308nm准分子激光治疗斑秃42例疗效观察

Clinical efficacy of 308 nm excimer laser in the treatment of 42 alopecia areata patients

目的 观察308nm准分子激光治疗斑秃临床疗效及安全性。方法：试验组用308nm准分子激光对42例斑秃患者进行每周2～3次照射治疗并观察疗效。对照组：用浓度为5mg／mL的曲安奈德液头部皮损内注射，注射4～6周后观察疗效。结果试验组与对照组差异具有统计学意义，试验组疗效好于对照组。试验组中有2例患者经过308nm准分子激光5次后即有效，其余治疗有效患者中平均照射次数9．1次。结论308nm准分子激光治疗斑秃安全，有效，患者依从性较高。

Objective To observe the clinical efficacy and safety of 308 nm excimer laser treat alopecia areata patients. Methods 42 alopecia areata patients as test group are treated with 308 nm excimer laser 2-3 times a week and observe the effect of radiation treatment. 30 alopecia areata patients as Control group are treated by injectting the concentration of 5 mg/mL triamcinolone acetonideion fluid in the head lesions,4-6 weeks later observed effect. Results Test group and control group have statistically significant difference. Efficacy of the test group was better than the control group In test group two patients get Effective treatment after five times with 308 nm excimer laser treatment. The rest of the effective treatment of patients can get Effective treatment with an average of 9. 1 times. Conclusion 308 nm excimer laser treat alopecia areata are more safe and effective, and patients have high compliance.