急性脑血管病合并睡眠呼吸暂停综合征的临床研究

Clinic research on patients with acute CVD combined with SAS

目的分析急性脑血管病(CVD)患者合并睡眠呼吸暂停综合征(SAS)的发生率和类型,探讨脑血管病(CVD)合并SAS事件的发病机制。方法随机抽取急性CVD患者82例,利用多导睡眠图(PSG)进行睡眠呼吸监测,观察睡眠呼吸监测指标。结果(1)82例急性CVD患者中存在SAS者61例(74.39%),其中阻塞性睡眠呼吸暂停综合征(OSAS)40例(65.57%),混合性睡眠呼吸暂停综合征(MSAS)14例(22.95%),中枢性睡眠呼吸暂停综合征(CSAS)7例(11.48%);(2)急性CVD患者中存在SAS组的呼吸暂停低通气指数、低氧时间、平均和最低血氧饱和度与不存在SAS组差别显著(P<0.01)。结论SAS与CVD关系密切,认为SAS是CVD被忽视的危险因素,但不排除CVD诱发了SAS的可能,两者形成恶性循环,影响CVD康复。

Objective To analyse occurrence rate and type of which patients with acute CVD combined with SAS, and study the pathogeny of acute CVD combined with SAS matters. Methods 82 cases of acute CVD were selected at random, Polysomnographic studies were performed. Results 61 cases （74. 39%） were Combined with SAS among 82 cases of Acute CVD, which 41） cases （65.57%） were obstructive, 14 cases （22. 95 %） were mixing and 7 cases （11. 48% ） were central type. Sleep apnea hypoventilation index, hypoxemic time,mean and lowest blood oxygen saturation ratio of patients with acute CVD combined with SAS and were also different markedly with that of non - combined with SAS（P〈0. 01 ）. Conclusions There is a close relationship between SAS and CVD , SAS is a neglected risk factor of CVD , but might also be the result of them. An vicious circle might be formed between CVD and SAS , and inflenees the outcome of CVD.