比较Episure^TM AutoDetect^TM注射器和玻璃注射器用于判断产妇硬膜外间隙的先导研究

Episure^TM AutoDetect^TM注射器是一种内置弹簧的新型注射器，由于注射器内部使用压缩弹簧对针栓保持了持续的压力，能够自动检测硬膜外穿刺过程中的阻力丧失。本项先导研究在接受硬膜外镇痛的产妇中，比较了使用Episure^TM AutoDe-tect^TM注射器和标准玻璃注射器判断穿刺进入硬膜外间隙的准确性。初级观察指标为硬膜外镇痛失败的发生率。研究共纳入325例产妇。其中291例（90％）硬膜外镇痛操作由8名住院医师实施，其余34例（10％）由2名主治医师实施。玻璃注射器组中有5例硬膜外镇痛失败，Episure^TM AutoDetect^TM注射器组无一例硬膜外镇痛失败（P=0．025）。

The Episure^TM AutoDetect^TM syringe, a spring-loaded syringe, is a new loss-of-resistance syringe with an internal compression spring that applies constant pressure on the plunger. In this pilot study, we compared the spring-loaded syringe with the standard glass syringe for identification of the epidural space during initiation of epidural analgesia in parturients. The primary outcome was the incidence of failed epidural analgesia. Three-hundred and twenty-five women were enrolled. Eight residents performed 291 procedures （90%） and two attendings performed 34 procedures （ 10% ）. Epidural analgesia failed in five subjects in the glass syringe group and in no subject in the spring-loaded syringe group （P = 0. 025）.