多重动脉粥样硬化危险因素与冠状动脉病变特征

Relationships between the multiple-risk factors of atherosclerosis and the serious degree of coronary artery disease

目的:研究多重动脉硬化危险因素与冠状动脉病变严重程度的关系。方法:根据病史询问、体格检查和血脂、血糖测定情况确定冠状动脉危险因素,并根据危险因素分为多重危险因素组及对照组。用冠状动脉造影术确定冠状动脉病变严重程度。结果:多重危险因素组较对照组冠状动脉病变严重,其冠状动脉多支病变率和平均病变支数明显高于对照组(P<0.05～<0.01)。结论:多重危险因素聚集往往导致冠状动脉的病变,并影响其病变范围。

Objective： To investigate the relationships between the multiple-risk factors of atherosclerosis and the seri ous degree of coronary artery disease. Methods： The risk factors of atherosclerosis was determined after enquiring about medical history, health checkup, and measured the levels of plasma serum lipid and blood glucose. The patients were assigned to multiple-risk factors group （risk factor≥3） or controls group （risk factor〈3）. The serious degree of coronary artery disease was determined using coronary angiography. Results： There was more serious degree of coronary artery disease in the multiple-risk factors group than that of controls group, the multiple vessel lesions and average vessels with lesion in the multiple-risk factors group were more than those of control group （P〈0.05〈0.01）. Conclusion ： The coronary artery disease often is the result of multiple-risk factors of atherosclerosis and its scope is determined by multiple-risk factors of atherosclerosis.