原发性肝癌患者血清中AFP检测的临床意义

Clinical Significance of Serum AFP Detection in Patients with Primary Carcinoma of Liver

目的探讨血清中甲胎蛋白(AFP)在原发性肝癌诊断中的应用价值。方法免疫分析法测定血清中AFP。结果原发性肝癌AFP极度增高。肝病患者以AFP>400μg/L作为界值诊断原发性肝癌的灵敏度为73.49%,特异性达99.32%。结论AFP是诊断原发性肝癌的重要的免疫学指标,动态观察AFP水平有助于鉴别肝癌与非肝癌性肝病。

[ Objective ] To investigate the application value of AFP in the diagnosis of primary carcinoma of liver. [ Methods ] Immunoassay was adopted to determine serum AFP. [ Results ] AFP extremely increased in patients with primary carcinoma of liver. Taking AFP 〉 400 μg/L as the critical value for hepatopathy patients, the sensitivity and specificity of diagnosed primary carcinoma of livers were 73.49% and 99.32%. [ Conclusion] AFP is the important immunology indicator in diagnosing primary carcinoma of liver. Dynamic observation of AFP levels contributes to the identification of liver carcinoma and non-carcinoma liver disease.