线粒体天冬氨酸氨基转移酶的测定在心、肝疾病诊治中的意义

Value on Determination of Mitochondrial Aspartate Aminotransferase for Diagnosis and Treatment of Heart or Liver diseases

目的探讨线粒体天冬氨酸氨基转移酶(m-AST)测定在心、肝疾病诊治中的作用。方法选取100例心肝疾病患者,分急性心肌梗死、病毒性心肌炎、肝硬化、肝炎4组测定AST和m-AST值,与正常组进行对比。结果各观察组的AST和m-AST的测定值与正常组比较,差异有统计学意义(P<0.01)。结论m-AST同工酶测定对心、肝疾病的诊治具有较高的临床价值。

[ Objective] To discuss the value of determination of mitochondrial aspartate aminotransferase （ m AST ） for diagnosis and treatment of heart or liver diseases. [ Methods ] 100 cases of heart or liver diseases were divided into acute myocardial infarction group, viral myocarditis group, liver cirrhosis group and hepatitis group. The AST and m AST value of patients were determined and compared with that of the normal group. [ Results] The differences in AST and m AST value between each observation group and normal group were significant（ P 〈 0.01 ）. [ Conclusion] The determination of m AST isozyme is with high clinical value for the diagnosis and treatment of heart or liver diseases.