期刊文献+

促红细胞生成素对慢性肾功能不全患者心功能的影响 被引量:2

下载PDF
导出
摘要 目的观察促红细胞生成素(EPO)对慢性肾功能不全(CRF)患者心功能的影响,并探讨其机制。方法将60例CRF并贫血、心功能不全者分为两组,观察组采用EPO联合铁剂治疗,对照组仅予铁剂,均治疗6个月。结果治疗后观察组心功能显著改善(P<0.05),而对照组无明显变化。结论EPO联合铁剂治疗可改善CRF患者心脏功能。
出处 《山东医药》 CAS 北大核心 2009年第15期71-71,共1页 Shandong Medical Journal
  • 相关文献

参考文献3

  • 1陈燕,刘志红.促红细胞生成素在急性肾小管损伤中的保护作用[J].肾脏病与透析肾移植杂志,2005,14(4):361-363. 被引量:5
  • 2Besarab A, Bolton WK, Rrowne JK, et al. The effect of normal as compared with low henmtoerit values in patients with cardiac disease who are receiving hem odialysis and e rythropoictin [ J ]. N Engl J Med,1998,27(9) :584-590.
  • 3Smith KJ, Bleyer AJ, Little WC, et al. The cardiovascular effects of erythropoiet in[ J]. Cardiovascular Research,2003,59 ( 9 ) :538.

二级参考文献19

  • 1Paixao AD, Ferreira AT, Oshiro ME, et al. Renal hemodynamic response to erythropoietin-induced policythemia in 5/6 nephrectomised rats is different from normal rats. Exp Nephrol, 1998,3:245-252.
  • 2Nemoto T, Yokota N, Keane WF, et al. Recombinant erythropoietin rapidly treats anemia in ischemic acute renal failure. Kidney Int, 2001,59: 246-251.
  • 3Nushiro N, Sakamaki T, Misawa S, et al. The effects of intrarenal infusion of recombinant human erythropoietin on renal hemodynamics and renal function in anesthesiazed rabbits. Nippon Jinzo Gakhai Shi,1993,35:125-131.
  • 4Jelkmann W. Erythropoietin: Structure, control of production, and function. Physiol Rev,1992,72: 449-489.
  • 5Tan CC, Eckardt KU, Firth JD, et al. Feedback modulation of renal and hepatic erythropoietin mRNA in response to graded anemia and hypoxia. Am J Physiol,1992,263: F474-F481.
  • 6Bernaudin M, Bellail A, Marti HH, et al. Neurons and astrocytes express brain EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain. Glia, 2000,30(3): 271-278.
  • 7Westenfelder C. Unexpected renal actions of erythropoietin. Exp Nephrol, 2002,10: 294-298.
  • 8Siren AL, Fratelli M, Brines M, et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci USA, 2001,98:4044-4049.
  • 9Grimm C, Wenzel A, Groszer M, et al. HIF-1-induced erythropoietin in the hypoxic retina protects against light-in-duced retinal degeneration. Nature Med, 2002,8: 718-724.
  • 10Carnot P, DeFlandre C. Sur l'activite hemopoietique de serum au cours de la regeneration du sang. C R Acad Sci (Paris),1906,143:384-386.

共引文献4

同被引文献40

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部