少枝胶质细胞瘤的病理分级及鉴别诊断

Pathologic Grading and Differential Diagnosis on Oligodendroglioma

用光镜及免疫组化观察了６５例少枝胶质细胞瘤（以下称ＯＤＧ）的组织学特性，根据ＷＨＯ有关ＯＤＧ的病理分级，发现该６５例中Ⅰ级１９例，Ⅱ级３２例，Ⅲ级１４例。结果表明ＯＤＧ病理分级除按瘤细胞分化程度外，细胞密度、核分裂数及凋亡细胞灶性聚集亦有重要意义。

To investigate the histological characteristics of oligodendroglioma (ODG),65 cases of ODG were observed with light microscopy and partially with immunohistochemistry.According to WHO classification of tumors,65 cases of ODG were graded in degree of differentiation of tumor cells.Of these,19 cases belonged to grade I,32 grade Ⅱ,and 14 grade Ⅲ.Conclusion:Except the degree of differentiation,some other criterions as cellular density,mitotic activities,and the presence of focally concentrated apoptotic cells are closely related to grading of ODG.