闭合性颅脑损伤后神经源性肺水肿的回顾性研究

A Retrospective Study of Neurogenic Pulmonary Edema Following Intracranial Injury Without Open Wound

为探索闭合性颅脑损伤后神经源性肺水肿的有关因素，对３４例闭合性颅脑损伤死亡案例尸解资料进行了回顾性研究。结果显示神经源性肺水肿发生率为４１．１８％。３４例颅脑损伤案例中以１０～４９岁为多见，该年龄段神经源性肺水肿发生率为４４．４４％；颅脑损伤后立即死亡至损伤后６小时内死亡者神经源性肺水肿发生率为４１．１８％，伤后７小时至４８小时死亡者神经源性肺水肿发生率亦为４１．１８％；单一部位损伤出血者神经源性肺水肿发生率为６９．２３％，多部位损伤出血者神经源性肺水肿发生率为２３．８１％。结论：颅脑损伤后神经源性肺水肿的发生与损伤后经历时间及脑损伤部位无关，但与脑损伤严重程度有关。

To find factors that relate to the occurrence of neurogenic pulmonary edema(NPE) following intracranial injury without open wound,thirtyfounr autopsies on such cases were studied retrospectively.The rate of NPE in the 34 cases was 41.18%,and it was 44.44% in those aged 10 to 49.The rate of NPE in the persons who died immediately or 06 hours after injury was 41.18%,and in those who died 748 hours after injury,41.18% too.The rate of NPE was 69.23% for the cases with only one site of bleeding and 23.81% for ones with multiple sites of bleeding.These findings suggest that the occurrence of NPE is not related with the duration of time after head injury or the location of brain injury,but it is related with the severity of brain injury.