摘要
目的探讨高血压患者血压近日节律的特点与发生脑血管意外并发症的关系。方法收集发生脑出血及脑梗塞高血压患者一般资料和检测24 h动态血压,并按脑出血和脑梗塞分组,使用余弦法(包括单余弦法MSC和群体余弦法MPC)分析各自血压近日节律特点,并作统计学处理。结果使用MSC和MPC分析均发现,两组年龄、性别、血脂等一般情况无差异的状况下,其血压近日节律的相位和调整中值亦无显著差异,其节律式样的不同主要表现在脑梗塞组的血压近日节律振幅较脑出血组的血压近日节律的振幅偏低。结论血压的近日节律变化与高血压患者脑血管意外的发生相关,使用余弦分析法能够较好地评价这种近日节律变化,血压近日节律振幅高的高血压患者发生脑出血的危险较大。
Obiective To investigate the different blood-pressure circadian characters of hypertension patients with different type cerebral vascular accident in Chinese. Methods Hypertension was the strongest risk factor for primary cerebral vascular accident. General data and 24 h dynamic blood pressure of hypertension patients were collected and classified into cerebral hemorrhage and cerebral infarction groups. An analysis way of cosine method ( MSC and MPC) was used statistically to analyze the different circadian rhythm of blood pressure of hypertension patients with different type primary cerebral vascular accident. Results It was found there was no difference in mesor and phase of blood-pressure circadian rhythm between cerebral hemorrhage group and cerebral infarction group under no difference in data of age, sex and blood lipid. But the amplitude of cerebral hemorrhage group was higher than cerebral infarction group. Conclusion In hypertension patients, the changes of circadian rhythm of blood pressure are related with the recurrence of their cerebral vascular accident. These changes of blood pressure circadian rhythm can be better evaluated with cosine method. Higher amplitude change of blood pressure circadian rhythm, more risk of cerebral hemorrhage occurs in hypertension patients.
出处
《航天医学与医学工程》
CAS
CSCD
北大核心
2009年第2期102-105,共4页
Space Medicine & Medical Engineering
基金
国家自然科学基金资助(3997027530070288)
关键词
脑出血
脑梗塞
近日节律
余弦法
高血压
cerebral hemorrhage
cerebral infarction
circadian rhythm
cosine method
hypertention