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老年结肠癌线粒体DNA微卫星不稳定情况分析

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摘要 目的:观察老年结肠癌线粒体DNA微卫星不稳定(mtMSI)情况。方法:选择老年结肠癌48例,采用限制性多态性方法检测结肠癌组织,并与正常组织比较。结果:48例中检出mtMSI9例(18.8%),主要发生于D-loop区。结论:mtMSI可能是结肠癌发生过程中的早期事件,在部分结肠癌发生过程中起一定作用。
机构地区 第三军医大学
出处 《人民军医》 2009年第5期296-297,共2页 People's Military Surgeon
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