中长链脂肪酸食用油对不同程度高甘油三酯血症患者体脂的影响

Effect of Dietary Medium-and Long-chain Triacylglycerols on Body Fat Accumulation in Subjects with Different Levels of Hypertriglyceridemia

目的观察中长链脂肪酸食用油对不同程度的高甘油三酯血症患者体脂的影响。方法将112例高甘油三酯血症患者随机分为两组,分别食用含长链脂肪酸和中长链脂肪酸的食用油,于试验前及试验8周后分别测量身高、体重、腰围、臀围、三头肌皮褶厚度、肩胛下皮褶厚度、体内脂肪重量、脂肪百分比、腹部总脂肪面积、内脏脂肪面积和皮下脂肪面积及血中甘油三酯(TG)水平,并计算体质指数(BMI)、腰臀比,组内以TG2.3mmol/L为界分层,比较试验前后上述指标两组间的差异。结果食用中长链脂肪酸食用油8周后,与食用长链脂肪酸食用油相比,TG≤2.3mmol/L者的体重、BMI、腰围、体内脂肪重量、腹部总脂肪面积、内脏和皮下脂肪面积均降低(P<0.05),而TG>2.3mmol/L者的所有人体测量指标两组间均无统计学意义;此外,食用中长链脂肪酸食用油8周后高甘油三酯血症患者血中TG水平均降低(P<0.05)。结论合理使用中长链脂肪酸食用油可使TG≤2.3mmol/L的高甘油三酯血症患者的体脂降低,但对TG>2.3mmol/L者降低体脂的效果不明显。

Objective To investigate the effect of medium- and long-chain triacylglycerols on body fat accumulation in subjects with different levels of hypertriglyceridemia. Methods 112 subjects with hypertriglyceridemia were randomly divided into two groups： one group was demanded to adopt long-chain triacylglycerol （LCT） oil as their daily use and the other one to medium- and long-chain triacylglycerol （MLCT） oil for consecutive 8 weeks. Anthropometric measurements of body weight, body mass index （BMI）, waist circumference （WC）, hip circumference（HC）, WHR （ratio of WC/HC）, triceps skinfold thickness （TSF）, subscapular skinfold thickness （SSF）, body fat weight, body fat percentage, total fat area, visceral and subcutaneous fat area in abdominal and concentration of blood triglycerides （TG） were measured at the initial and final time of the study. In both groups, the cutpoint of TG 2.3 mmol/L was used to distinguish the different levels of hypertriglyceridemia. Results Compared with LCT group, body weight, BMI, WC, body fat weight, total fat area, visceral and subcutaneous fat area in abdominal in those of TG ≤ 2.3 mmol/L in MLCT group were significantly decreased （P〈0.05）, while no significant differences were observed in those of TG〉2.3 mmol/L between the two groups. Furthermore, the concentrations of TG in hypertriglyceridemia subjects of different levels in MLCT group were both significantly lower than those in LCT group after 8 weeks （P〈0.05）. Conclusion Medium- and long-chain triacylglycerols may help to reduce body fat accumulation in hypertriglyceridemia subjects of TG ≤ 2.3 mmol/L under an appropriate dietary regime, but the effect was not evident in those of TG〉 2.3mmol/L.