抗抑郁治疗的临床现状

Clinical Status of Antidepressant Treatment

抑郁症的治疗分为药物治疗和非药物治疗。药物治疗包括三环类、四环类抗抑郁剂、五-羟色胺再摄取抑制剂、5-羟色胺(5-HT2)受体拮抗及5-HT重吸收抑制剂、去甲肾上腺素及多巴胺重吸收抑制剂、5-HT及去甲肾上腺素重吸收抑制剂,去甲肾上腺素能和特异性5-HT能抗抑郁药以及增效剂的辅助治疗;非药物治疗包括心理治疗、电休克治疗、经颅磁刺激及深部脑刺激治疗,在临床上多项研究为抑郁症患者提供了希望。

Treatment of depression is divided into drug treatment and non-drug treatment. Drug therapy including tricyclic, tetracyclic antidepressant category,Serotonin reuptake inhibitors （SSRI）,Serotonin receptor antagonist and re-absorption inhibitors （SARl）,norepinephrine and dopamine reuptake inhibitors （NDRI）, serotonin and norepinephrine reuptake inhibitors （SNRI）, norepinephrine and specific serotonergic antidepressants （NaSSA） and synergist to support treatment; Non-drugs treatments include psychotherapy, electric shock therapy,transcranial magnetic stimulation （TMS） and deep brain stimulation （DBS）treatment.In clinical practice for a number of studies provide hope that patients with depression.