Determination of ephedrine and codeine in human urine by cation-selective exhaustive injection and sweeping micellar electrokinetic chromatography

为在由毛状的电气泳动(CE ) 的人的尿的麻黄素和 codeine 的决心的一个敏感方法被描述。为了改进敏感，包括阳离子选择的彻底的注射(CSEI ) 的二种联机集中技术和大规模 micellar 电镀物品，运动层析(sweeping-MEKC ) 被使用。在最佳条件下面，察觉限制(S/N = 3 ) 是 0.10 &#x3bc；为麻黄素和 0.80 &#x3bc 的 g/L；为 codeine 的 g/L。这个方法成功地被用于真实的尿样品分析。

A sensitive method for the determination of ephedrine and codeine in human urine by capillary electrophoresis （CE） was described. In order to improve the sensitivity, two online concentration techniques including cation-selective exhaustive injection （CSEI） and sweeping micellar electrokinetic chromatography （sweeping-MEKC） were used. Under the optimum conditions, the detection limits （S/N = 3） were 0.10 μg/L for ephedrine and 0.80 μg/L for codeine. This method was successfully applied to real urine sample analysis.