乳腺癌超声造影表现

Contrast-enhanced ultrasound findings of breast cancer

目的探讨不同大小乳腺癌的超声造影表现。方法84例乳腺癌术前行超声造影检查,其中肿块最大直径>2.0cm病例共50例,最大直径≤2.0cm病例共34例;所有病例均应用时间-强度曲线分析软件测定定量参数,并分析时间-强度曲线类型,以及肿块增强模式,分析不同大小肿块超声造影间的差别。结果在不同大小的乳腺癌病例中,最大直径≤2.0cm及直径>2.0cm乳腺癌的基础强度、峰值强度、强化强度、上升斜率、强化强度指数以及曲线类型间差异无统计学意义(P>0.05);增强模式间差异有统计学意义(P<0.01)。结论最大直径≤2.0cm与直径>2.0cm乳腺癌超声造影增强模式存在差别。造影诊断乳腺癌时应根据肿瘤的大小区别分析。

Objective To study the manifestation of breast cancers of different sizes in contrast-enhanced sonography. Methods Eighty-four patients with breast cancers were examined by contrast-enhanced ultrasound. Among them, the tumor diameter was beyond 2.0 cm in 50 cases, and no greater than 2.0 cm in the rest cases. The time-intensity curve （TIC） on the enhanced images was analyzed quantitatively, and the relations between the type of TIC and the enhancement patterns of the tumors were analyzed. Results The enhancement patterns of the breast cancers showed significant difference between patients with tumor diameter beyond 2.0 cm and those with smaller tumors （P〈0.01）, but the other parameters were comparable between the two groups （P〉0.05）. Conclusion The enhancement patterns of breast cancers differ between tumors with sizes over 2.0 cm and smaller tumors, and differential analysis is suggested in the diagnosis of breast cancer using contrast-enhanced ultrasound.