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大鼠窒息法心脏骤停后心肌挛缩的发生规律 被引量:4

Features of ischemic myocardial contracture after asphyxia-induced cardiac arrest in rats
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摘要 目的探讨心脏骤停后缺血性心肌挛缩的发生规律。方法通过测量Wistar大鼠心脏骤停后心脏长度、宽度的变化,分析窒息法心脏骤停后心肌挛缩的发生规律。结果窒息法致心脏骤停后大鼠心脏均出现明显的心肌挛缩现象,在心脏骤停后4~6min心肌挛缩程度接近最大。结论窒息法心脏骤停模型大鼠发生心肌挛缩时间早,对及时复苏可能要求更高。 Objective To investigate the features of ischemic myocardial contracture after asphyxial cardiac arrest in rats. Methods Asphyxial cardiac arrest was induced in 8 Wistar rats, and the length and width of the heart were measured at the different time points after cardiac arrest. Results Obvious ischemic myocardial contracture occurred after the cardiac arrest, reaching the maximal contracture at 4-6 min after the arrest. Conclusion Ischemic myocardial contracture induced by asphyxia may be an important factor affecting the outcome of cardiopulmonary resuscitation.
出处 《南方医科大学学报》 CAS CSCD 北大核心 2009年第4期787-790,共4页 Journal of Southern Medical University
关键词 窒息 心肺复苏 心肌挛缩 asphyxia ischemic myocardial contracture cardiopulmonary resuscitation
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