丹参联合易善复对肝炎合并肝癌术后残肝的临床研究

Effects of essentials plus red saqe root on virus hepatitis complicated with liver cancer

目的评价丹参联合易善复干预肝炎后肝癌术后残肝的临床疗效。方法选择病毒性乙型肝炎合并肝癌患者72例,随机分为2组。对照组32例,采用口服益肝灵、维生素类护肝药、静脉滴注能量合剂、门冬氨酸钾镁,酌情应用氨基酸、白蛋白等治疗。治疗组40例,在对照组治疗基础上应用易善复和复方丹参片治疗,均2个月为1个疗程。观察2组治疗效果。结果治疗组总有效率为97.5%明显高于对照组的62.5%,差异有统计学意义(P<0.01)。治疗组肝功能(ALT、TST、TBiL)、肝癌指标及临床症状等项目的改善均明显优于对照组(P<0.01或P<0.05),且无明显不良反应。结论丹参联合易善复治疗病毒性肝炎合并肝癌对促进肝脏脂类代谢、降低病毒复制量、修复损伤的肝细胞及阻止或改善肝癌均有明显的功效。

Objective To evaluate the therapeutic effect essentials and red saqe root on virus hepatitis merging hepatic fibrosis. Methods 72 patients with virus hepatitis complicated with liver cancer were divided into therapeutic group （ n = 40） and control group（ n = 32） randomly. Patiens of the two groups were all given specific treatment. The course of therapy is 2 months. Results There were significant difference in total effeciency between two groups（97.5% vs 62.5%, P 〈 0.01 ）. ALT, TBiL, hepatic fibrosis and clinical symptom in therapeutic group were obviously improved. There was significant difference between the two groups. （ P 〈 0.05 or P 〈 0.1 ） and there were no obviously vice - reaction. Conclusion Essentials plus red saqe root can promote the grease＇s metabolism of liver , repair damage of hepatic cell and prevent the progress of hepatic fibrosis.