生脉注射液对重症胰腺炎的辅助治疗研究

The effect of Shengmai injection as an adjutant therapy on severe pancreatitis

目的探讨生脉注射液对重症胰腺炎(SP)的治疗作用,以提高重症胰腺炎的疗效。方法35例重症胰腺炎患者分成2组,治疗组20例,对照组15例。2组SP患者均先行急诊手术治疗,术后按常规处理,其中治疗组术后加用生脉注射液。结果2组患者的临床表现、检验、手术和病理及并发症,差异无统计学意义(P>0.05)。治疗组的病死率为10.0%,对照组病死率33.3%,2组比较差异有统计学意义(P<0.05)。治疗组红细胞压积(Ht)从术前的(47.8±5.2)%降低到(32.6±3.4)%,差异有统计学意义(P<0.05);血小板计数(PLT)和血红蛋白(Hb)的变化无统计学意义(P>0.05)。结论生脉注射液在以手术为主的中西医结合治疗SP中有重要的临床价值。

Objective To investigate the effect of shengmai in serve pancreatitis and to improve the curative effect in SP. Methods 35 patients were divided into two groups： Except the trial group （20 patients） was injected with shengmai post- operatively, the other therapies were as same as that of the control group （15 patients）, and both the clinical manifestation, lab test, operation, pathological report and complication have no statistical significance. Results There were no difference in clinical symptom, detection and operation between two groups （ P 〉 0.05 ） The mortality （ 10.0% ） of the trial group was significantly lower than that（33.3% ） or the Control group（P 〈0.05） ,and its Hematocrit was obvious decreased from 47.8% ±＋ 5.2% to 32.6% ±3.4% （P 〈 0.05 ）. but platelet and hemoglobin showed no statistical significance. Conclusion The modern treatment to SP is based upon its evidence of medicine, Shengmai injection is very important in treatment of SP combined with classical methods.