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利多卡因复合地塞米松抑制芬太尼咳嗽反射 被引量:3

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摘要 目的观察利多卡因复合地塞米松抑制芬太尼咳嗽反射的效果。方法选择全麻患者320例,随机分为实验组(LD组)、利多卡因组(L组)、地塞米松组(D组)和对照组(NS组)各80例。LD组在注射芬太尼前10 min静注利多卡因1 mg/kg及地塞米松5 mg,L组静注等容量的利多卡因1 mg/kg,D组静注等容量的地塞米松5 mg,NS组静注等量的生理盐水。观察4组患者注射芬太尼1 min后反射性咳嗽的发生率。结果LD组反射性咳嗽发生率9%,L组发生率21%,D组发生率22%,NS组发生率40%。LD组与NS组比较有极显著性差异(P<0.01),与L、D组比较有显著性差异(P均<0.05)。结论利多卡因复合地塞米松能够有效地抑制芬太尼反射性咳嗽。
出处 《现代中西医结合杂志》 CAS 2009年第14期1655-1656,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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二级参考文献2

  • 1Lin CS,Sun WZ,Chan WH,et al.Intravenous lidocaine and ephedrine,but not propofol,suppress fentanyl-induced cough.Can J Anaesth,2004,51:654-659.
  • 2Agarwal A,Azim A,Ambesh S,et al.Salbutamol,beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl.Can J Anaesth,2003,50:297-300.

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