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Galectin-1在头颈部鳞状细胞癌中的研究进展

Galectin-1 and Squamous Cell Carcinoma of the Head and Neck
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摘要 头颈部鳞状细胞癌(head and neck squamous cell carcinoma,HNSCC)是常见的头颈部疾病,其发病率居恶性肿瘤第六位。目前,手术联合放疗、化疗是HNSCC的主要治疗手段。肿瘤免疫治疗是在现代肿瘤免疫学理论的基础上。结合免疫生物学、分子生物学等诸学科的发展而形成的一种治疗手段。因为其效果明显且副作用小,成为综合治疗最主要的辅助手段并广泛应用于临床。
出处 《口腔颌面外科杂志》 CAS 2009年第2期134-136,共3页 Journal of Oral and Maxillofacial Surgery
关键词 头颈部鳞状细胞癌 GALECTIN-1 肿瘤免疫 HNSCC Galectin-1 tumor immunity
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参考文献21

  • 1Ferris RL. Progress in head and neck cancer immunotherapy: can tolerance and immune suppression be reversed [J]. ORL J Otorhinolaryngol Relat Spec, 2004, 66(6):332- 340.
  • 2程杰,王佐林.肿瘤干细胞研究进展[J].口腔颌面外科杂志,2006,16(3):263-266. 被引量:1
  • 3Camby I, Lemercier M, Lefranc F, et al. Galectin-1: a small protein with major functions[J]. Glycobiology, 2006, 16(11): 137R- 157R.
  • 4Perillo NL, Pace KE, Seilhamer JJ, et al. Apoptosis of T cells mediated by Galectin-1[J]. Nature, 1995, 378(6558): 736-739.
  • 5Liu FT, Rabinovich GA. Galectins as modulators of tumor progression[J]. Nat Rev Cancer, 2005, 5(1):29-41.
  • 6Sotomayor CE, Rabinovich GA. Galectin-1 induces central and peripheral cell death: implications in T-cell physiopathology[J]. Dev Immunol, 2000, 7(2-4):117-129.
  • 7Garin MI, Chu CC, Golshayan D, et al. Galectin-1: a key effector of regulation mediated by CD4^+CD25^+ T cells[J]. Blood, 2007, 109(5):2058-2065.
  • 8He J, Baum LG. Presentation of galectin-1 by extracellular matrix triggers T cell death[J]. J Biol Chem, 2004, 279(6): 4705-4712.
  • 9Matarrese P, Tinari A, Mormone E, et al. Galeetin-1 sensitizes resting human T lymphoeytes to Fas (CD95)-mediated eell death via mitoehondrial hyperpolarization, budding, and fission[J]. J Biol Chem, 2005, 280(8):6969-6985.
  • 10Rabinovich GA. Galectin-1 potential cancer target[J]. Br J Cancer, 2005, 92(7):1188-1192.

二级参考文献31

  • 1Fang D,Nguyen TK,Leishear K,et al.A tumorigenic subpopulation with stem cell properties in melanomas[J].Cancer Res,2005,65 (20):9328-9337.
  • 2Collins AT,Berry PA,Hyde C,et al.Prospective identification of tumorigenic prostate cancer stem cells[J].Cancer Res,2005,65 (23):10946-10951
  • 3Zhou S,Schuetz JD,Bunting KD,et al.The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the sidepopulation phentotype[J].Nat Med,2001,7 (9):1028-1034.
  • 4Kondo T,Setoguchi T,Taga T Persistence of a small subpopulation of cancer stem-like cells in C6 glioma cell line[J].Proc Natl Acad Sci USA,2004,101(3):781-786.
  • 5Chen JS,Pardo FS,Wang-Rodriguez J,et al.EGFR regulates the side population in head and neck squamous cell carcinoma[J].Laryngoscope,2006,116(3):401-406.
  • 6Cozzio A,Passegué E,Paul MA,et al.Similar MLL-associated leukemias arising from self-reviewing stem cells and short-lived myeloid progenitors[J].Genes Dev,2003,17(24):3029-3035.
  • 7Serakinci N,Guldberg P,Burns JS,et al.Adult human mesenchymal stem cell as a target for neoplastic transformation[J].Oncogene,2004,23(29):5095-5099
  • 8Reya T,Clevers H.Wnt signaling in stem cells and cancer[J].Nature,2005,434(7035):843-850.
  • 9Taipale J,Beachy PA.The hedgehog and Wnt signaling pathways in cancer[J].Nature,2001,411(6835):349-354.
  • 10Kerinek V,Nick B,Petra M,et al.Depletion of epithelial stem cell compartment in the small intestine of mice lacking TCF-4[J].Nature Genetics,1998,19(4):379-383.

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