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A new cytotoxic cardenolide from the latex of Antiaris toxicaria 被引量：1

A new cytotoxic cardenolide from the latex of Antiaris toxicaria
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摘要 A new cardenolide, toxicarioside E （1）, was isolated from the latex ofAntiaris toxicaria （Pers.） Lesch （Moraceae）. Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027 μg/mL, respectively. A new cardenolide, toxicarioside E （1）, was isolated from the latex ofAntiaris toxicaria （Pers.） Lesch （Moraceae）. Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027 μg/mL, respectively.
作者 Yu Juan Gan Wen Li Mei You Xing Zhao Hao Fu Dai
机构地区 Institute of Tropical Bioscience and Biotechnology State Key Laboratory
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2009年第4期450-452,共3页 中国化学快报（英文版）
基金 supported by National Natural Science Foundation of China(No.30860345) National Basic Research Program of China(No.2007CB116306 National Nonprofit Institute Research Grant of CATAS-ITBB(No.ITBBZD200744) the Natural Science Foundation of Hainan(Nos.80671,30608).
关键词 Antiaris toxicaria MORACEAE Toxicarioside E CARDENOLIDE CYTOTOXICITY Antiaris toxicaria Moraceae Toxicarioside E Cardenolide Cytotoxicity
分类号 Q959.133 [生物学—动物学] S794 [农业科学—林木遗传育种]
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参考文献7

  • 1N.G.Bisset. Lloydia . 1966
  • 2W.L.Mei,Y.J.Gan,H.F.Dai. Chin.Tradit.Herb.Drugs . 2007
  • 3M.M.Jiang,Y.Dai,H.Gao,et al. Chemical and Pharmaceutical Bulletin . 2008
  • 4A.C.Christine,W.F.Robert,A.C.Elizabeth,et al. Tetrahedron . 1997
  • 5Unon H T.Ethnopharmacol[]..1995
  • 6Yang Q,Xu M,Zhang Y,et al.Steroidal saponins fromDis-poropsis pernyi[].Helvet Chim Acta.2004
  • 7Mosmann,T. Journal of Immunological Methods . 1983

同被引文献23

  • 1Chun H Y(陈焕镛).Flora Hainanica Vol.2[M].Beijing:Science Press,1965:384-386.
  • 2Editorial Committee Members of the Administration of Bureau of Traditional Chinese Medicine.Chinese Material Medica Vol.2[M].Shanghai:Shanghai Science & Technology Press,1999:464-467.
  • 3Dai H F(戴好富).Records of Li Folk Medicine Vo1.2[M].Beijing:China Science and Technology Press,2010:16-17.
  • 4Wehrli W,Schindler O,Reichstein T.Die glykoside des milchsaftes von Antiaris toxicaria Lesch.aus Malaya sowie von Antiaris africana Engl.aus Kenya.Isolierungen[J].Helv Chim Acta,1962,45(4):1183-1205.
  • 5Wehrli W.Die glykoside des milchsaftes von Antiaris toxicaria Lesch.Konstitution ser mitteilung von Malayosid und α-Antiosid[J].Helv Chin Acta,1962,45(4):1206-1211.
  • 6Juslen C,Wehrli W,Reichstein T.Konstitution des antiarigenins und des antiosids vorlaugige mitteilung[J].Helv Chim Acta,1962,45(7):2285-2296.
  • 7Muhlradt P,Weiss E K,Reichstein T.Die cardenolide der samen von Antioris toxicaria Lesch.mitteilung:Isolierungen und identifizierungen[J].Helv Chim Acta,1964,47(8):2164-2185.
  • 8Bra(n)dt R,Kaufmann H,Reichstein T.Die cardenolide von Antiaris toxicaria Lesch.Identifizierung von《Bogorosid》 mit convallosid sowie isolierung und partialsynthese von gluco-periplor hamnosid[J].Helr Chim Acta,1966,49(8):2469-2481.
  • 9Carter C A,Forney R W,Gray E A,et al.Toxicarioside A.A new cardenolide isolated from Antiaris toxicaria latex-derived dart poison.Assignment of the 1H-and 13C-NMR shifts for an antiarigenin aglycone[J].Tetrahedron,1997,53(40):13557-13566.
  • 10Catter C A,Cray E A,Schneider T L,et al.Toxicarioside B and Toxicarioside C.New cardenolides isolated from Antiaris toxicaria latex-derived dart poison[J].Tetrahedron,1997,53 (50):16959-16968.

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Chinese Chemical Letters
2009年 第4期

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