摘要
目的探讨糖尿病患者血清胱氨酸蛋白酶抑制剂C(CysC)水平以及与早期肾脏损害的关系。方法采用免疫浊度法检测126例糖尿病患者及40例对照组血清CysC含量;采用苦味酸法检测上述对象的血清肌酐(Scr)含量。结果糖尿病组血清CysC及Scr水平均显著高于对照组(P<0.05),且年龄越大其CysC水平越高。结论血清CysC检测有助于了解糖尿病患者是否存在早期肾损害,对预防、治疗糖尿病肾病(DN)有重要意义。
Objective To explore the correlation of level of cystatin （CysC）with early damage to kidney in diabetic patients. Methods Immuno-nephelometry method was used to detect the level of CysC in 126 cases with diabetes mellitus and 40 cases of control group respectively. Picric acid method was used to detect the concentration of serum creatinine （Scr）. Results The Levels of CysC in diabetes mellitus patients were higher than that in control group apparently（P〈0.05）.The older the age of diabetes mellitus patients is,the higher the CysC level would be. Conclusions The detection of CysC is helpful for detection and treatment of early damage in kidney in diabetic patients.
出处
《中国热带医学》
CAS
2009年第5期859-859,870,共2页
China Tropical Medicine
