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非对称性2甲基精氨酸在心血管疾病中的应用进展 被引量：1

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摘要 非对称性2甲基精氨酸(asymmetric dimethylarginine,ADMA)作为内源性一氧化氮合酶(nitric oxide synthase,NOS)的抑制剂,近年来被证实与内皮功能不全有重要的相关性,同时在越来越多的横断面和前瞻性研究中发现其是心血管疾病的新的危险因子。
作者 莫与京 陈东骊 陈富荣
机构地区 广东省人民医院广东省医学科学院广东省心血管病研究所心内科
出处 《岭南心血管病杂志》 2009年第1期77-78,80,共3页 South China Journal of Cardiovascular Diseases
基金 广东省医学科学技术研究基金(A2008052)
关键词 精氨酸 一氧化氮合酶 心血管疾病 内皮细胞
分类号 R543 [医药卫生—心血管疾病]
  • 相关文献

参考文献14

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二级参考文献20

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共引文献18

同被引文献9

  • 1黄志宏,高燕燕.胰淀素与代谢综合征[J].国外医学（内分泌学分册）,2005,25(4):246-248. 被引量：2
  • 2金文胜,潘长玉.国际糖尿病联盟关于代谢综合征定义的全球共识[J].中华内分泌代谢杂志,2005,21(4):412-413. 被引量：155
  • 3Reaven GM. Relationships among insulin resistance, type 2 dia betes, essential hypertension, and cardiovascular disease: simi larities and differences [J]. J Clinical Hypertens (Greenwich) 2011, 13 (4): 238-243.
  • 4McLaughlin T, Stuhlinger M, Lamendola C, et al. Plasma asymmetric dimethylarginine concentrations are elevated in obese insulin-resistant women and fall with weight loss [-J. J Clin En docrinol Metab, 2006, 91 (5) 1896-1900.
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  • 6Fujii N, Tsuchihashi K, Sasao H, et al. Insulin resistance func- tionally limits endothelium dependent coronary vasodilation in nondiabetie patients f-J]. Heart Vessels, 2008, 23 (1): 9-15.
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  • 9刘玉岚.胰淀素基础与临床研究进展[J].承德医学院学报,2008,25(2):185-187. 被引量：2

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岭南心血管病杂志
2009年 第1期

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