坦索罗辛促进体外冲击波碎石后输尿管结石排出的临床分析

Clinical research of tamsulosin for the management of ureteral calculi after extracorporeal shock wave lithotripsy

目的评价坦索罗辛对体外冲击波碎石后输尿管结石排出的临床效果。方法166例输尿管结石的患者随机分成3组:A组在体外冲击波碎石后每天饮水2L,进行日常活动。B组除与A组相同外,口服普鲁本辛3次/d,15mg/次。C组除与A组相同外,每晚口服坦索罗辛0.4mg。观察结石排出率。结果体外冲击波碎石术后第1、3、7天,A组和B组患者碎石效率之间差异无统计学意义,P均>0.05;A组和C组之间的差异有统计学意义,P均<0.05;B组和C组之间的差异无统计学意义,P均>0.05。结论坦索罗辛有促进体外冲击波碎石后输尿管结石排出的作用。

Objective To evaluate the efficiency of tamsulosin for the patients with ureteral calculi after extraeorporeal shock wave lithotripsy. Methods A total of 166 patients with calculi located in the ureter were randomly divided into 3 groups. Group A served as controls;group B received probanthine （15mg, 3 times daily ） ;and group C received tamsulosin （0.4mg, once daily）. All patients were observed on 1,3,7 days after extracorporeal shock wave lithotripsy. Results Percentages of expulsion of calculi had no significant difference between group A and B, P 〉 0.05. Expulsion of calculi had significant diffrerence between group A and C, P 〈 0.05. Between group B and C, expulsion of calculi had no difference, P 〉 0.05. Conclusion It is demonstrated that tamsulosin is effective for expulsive treatment for ureteral calculi after extracorporeal shock wave lithotripsy.