低钠血症对肝硬化肝性脑病患者预后的影响

Influence of Hyponatremia on the Prognosis in Patients with Hepatic Encephalopathy

目的探讨肝硬化合并肝性脑病的患者血钠水平与肝功能及肝性脑病严重度的相关性。方法回顾性分析234例乙肝肝硬化合并肝性脑病患者的临床和实验室资料。结果乙肝肝硬化合并肝性脑病患者中有65.8%同时合并不同程度的低钠血症,肝硬化合并肝性脑病的患者,其血钠水平与肝功能及肝性脑病的严重度均具有相关性。结论血钠水平与肝性脑病严重度关系密切,血钠越低的患者其意识障碍程度越重。

Objective To explore the relationship between the level of natrum and liver function hepatic encephalopathy in liver cirrhosis patients with hepatic encephalopathy. Methods The clinical and laboratory data of 234 liver cirrhosis patients with hepatic encephalopathy were retrospectively analyzed. Results 65.8% patients accompanied with hyponatremia. The level of natrum had a closely relationship with liver function and the severity of hepatic encephalopathy in liver cirrhosis patients with hepatic encephalopathy. Conclusion The level of natnun showed correlation with liver function. The level of natrum was significantly lower in Child-pugh C group than that of B group. The level of natrum also related with the severity of hepatic encephalopathy. The degree of become serious with the decline of natrum.