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瑞芬太尼联合丙泊酚静脉全麻用于支撑喉镜手术的临床观察 被引量:6

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摘要 目的对比观察瑞芬太尼联合异丙酚与枸橼酸芬太尼联合异氟烷静吸复合麻醉对支撑喉镜手术的麻醉效果和麻醉恢复期的影响。方法ASAⅠ~Ⅱ级择期支撑喉镜手术患者40例。随机分为瑞芬太尼组(R组)和芬太尼组(F组)。每组20例,两组均以丙泊酚单次静注1.5~2.0 mg/kg,R组以瑞芬太尼单次静注1μg/kg,F组以枸橼酸芬太尼2.5μg/kg(插管前3 min单次静注)。意识消失后,氯琥珀胆碱1~1.5 mg//kg静注。随后行气管插管,机械通气。麻醉维持R组以静脉注射瑞芬太尼0.03μg/(kg.min)。丙泊酚7~8 mg/(kg.h)连续输液维持麻醉,F组以枸橼酸芬太尼0.1μg/(kg.min),吸入2%异氟烷维持麻醉。记录两组各时段生命体征(血压、心率、氧饱和度);麻醉恢复情况(自主呼吸恢复时间、睁眼时间、拔管时间、定向力恢复时间和离开恢复室时间)。观察患者拔管后即刻,离开恢复室(PACU)。拔管后30 min和1 h的意识状态(0AAS)。结果(1)两组在麻醉维持期间和麻醉恢复时间段血流动力学稳定,MAP、HR分别和其基础值相比差异无统计学意义(P>0.05);(2)自主呼吸恢复时间和离开PACU时间瑞芬太尼组早与对照组(P<0.05);(3)瑞芬太尼组在拔管后即刻,离开PACU,拔管后30 min,1 h OAAS评分高于对照组(P<0.05)。结论与常规静吸复合麻醉下行支撑喉镜手术相比瑞芬太尼复合异丙酚静脉麻醉具有麻醉平稳,苏醒快,可控性好的特点,是支撑喉镜手术麻醉的良好选择。
作者 刘春秋
出处 《临床军医杂志》 CAS 2009年第2期302-304,共3页 Clinical Journal of Medical Officers
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