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LYVE-1和VEGF-C在胃癌中的表达及与淋巴结转移的关系 被引量:2

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摘要 血管内皮生长因子-C(vascular endothelial growth factor—C,VEGF—C)和淋巴管内皮透明质酸受体-1(lymphatic vessel endothelial hyaluronanr eceptor-1,LYVE-1)都是淋巴管内皮细胞的标记物,其中LYVE-1是新近发现的较特异的淋巴管内皮细胞标记物。但目前国内外关于LYVE-1与肿瘤淋巴结转移之间关系的研究报道较少,也未见有关LYVE-1、VEGF—C表达的相互关系及与胃癌淋巴结转移的相关研究。本研究通过免疫组化染色,探讨VEGF—C和LYVE-1的表达在胃癌淋巴结转移过程中的作用和可能机制及其临床意义。
作者 崔健 杨勇明
出处 《浙江创伤外科》 2009年第2期104-106,共3页 Zhejiang Journal of Traumatic Surgery
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参考文献11

  • 1Breiteneder GS,Soleiman A,Kowalski H,et al.Podoplanin as a specific marker for lymphatic endothelium [J]. Am J Pathol, 1999,154(2):385-394.
  • 2Schoppmann S,Brirner P,Studer P,et al.Lymphatic microvessel density and lymphovascular invasion assessed by anti-podoplanin immunostaining in human breast cancer [J]. AnticancerRes, 2001,21 (4A):2351-2355.
  • 3Mattern J, Koommagi R, Volta M. Biological characterization of subgroups of squamous cell lung carcinomas [J]. Clin Cancer Res 1999,5:1459-1463
  • 4Alitalo K,Carmeliet P. Molecular mechanisms of lymphangiogenesis in health and disease [ J ]. Cancer Cell, 2002, 1 (3) :219-227.
  • 5Saharinen P, Tuomas T,Marika J, et al. Lymphatic vasculature: development,molecular regulation and role in tumor metastasis and inflammation [J ]. Trends Immunol, 2004,25 (7):387-395.
  • 6Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors [ J ]. Breast Cancer Res Treat, 1995,36( 1 ):69-73.
  • 7Howe LR, Dannenberg AJ. A role for eyelooxygenase-2 inhibitors in the prevention and treatment of cance [J]r. Semin Oncol , 2002,29 (3Suppl 11 ):111-119.
  • 8Fondevila C,Metges JP, Foster J, et al. p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer [J]. Br J Cancer,2004 , 90(1 ):206-215.
  • 9Banerji S, Ni J, Wang SX, et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph specific receptor for hyaluronan [J] . J Cell Biol, 1999,144:789-801.
  • 10Prevo R, Banerji S, Ferguson D J.Mousee LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium [J].J Biol Chem, 2001,276:420-430.

同被引文献20

  • 1邢光明,曲明阳,张桂平,冯秉安.胃癌组织中血管表皮生长因子C表达与血管和淋巴管生成及淋巴转移的关系[J].中华普通外科杂志,2004,19(6):361-363. 被引量:17
  • 2杨进强,李勇,范立侨,王益民,赵群,曹雷.VEGF-C及其受体VEGFR-3在胃癌淋巴转移中的作用[J].第二军医大学学报,2005,26(11):1256-1259. 被引量:9
  • 3张卫东,赵玲辉,张雅芳,郎庆玲,翁姗姗.胃癌组织淋巴管LYVE-1、钙粘蛋白的表达及其与癌转移的关系[J].中国临床解剖学杂志,2006,24(2):170-172. 被引量:7
  • 4Duskova J. Known pitfalls of the thyroid neoplasm diagnostics in the view of the new (2004) WHO Classification [ J ]. Cesk Patol,2006,42 (1) :24- 28.
  • 5Schoppmann SF, Birner P, Stockl J, et al. Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis [ J ]. Am Pathol, 2002,161 ( 3 ) : 947 -956.
  • 6Roskoski R Jr. Vascular endothelial growth factor(VEGF) signaling in tumor progression[J]. Crit Rev Oncol Hematol,2007,62 ( 3 ) : 179-213.
  • 7Kitadai Y, Amioka T, Haruma K. Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas[J].Int J Cancer,2001,93 (5) :662-666.
  • 8Onogawa S, Kitadai Y,Tanaka S, et al. Expression of VEGF-C and VEGF- D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma [ J 1. Cancer Science, 2004,95 ( 1 ) :32-39.
  • 9Zaydfudim V,Feurer I D,Griffin M R,et al.The impact of lymph node involvement on survival in patients with papillary and follicular thyroid carcinoma[J].Surgery,2008,144(6) : 1070-1077.
  • 10Vainionpaa N,Biitzow R, Hukkanen M, et al.Basement membrane protein distribution in LYVE-1-immunorcactive lymphatic vessels of normal tissues and ovarian carcinomas[J].Cell Tissue Res,2007,328 (2):317-328.

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