摘要
目的:探讨白质纤维束成像(Diffusion tensor tractography,DTT)技术在脑星形胶质细胞瘤研究中的价值。材料与方法:对33例经病理证实的脑星形胶质细胞瘤患者进行常规MR成像、弥散张量成像(DTI)和DTT,分析肿瘤瘤周白质纤维束的改变形式与肿瘤分级的关系。结果:无论是高级别还是低级别肿瘤,瘤周白质纤维束都可以发生移位(77.78%~100%),而白质纤维束的破坏和中断主要与星形胶质细胞瘤的恶性程度有关,随着肿瘤级别的升高,白质纤维束的破坏和中断的发生率也逐渐升高(7.69%~72.73%)。结论:DTT技术在显示脑星形胶质细胞瘤分级方面有重要的价值。
Objective: To evaluate the value of diffusion tensor tractography (DTT) in brain astrocytomas. Materials and Methods: Thirty-three patients with histologically confirmed astrocytomas underwent routine MRI, DTI, DTT, analyzing the changes of white matter fibres around the tumors and specific conditions in different grade of astrocytomas. Results: There is displacement of white matter fibres around tumors whether low-grade tumors or high-grade tumors (77.78%-100%). Disruption and interruption of white matter fibres around tumors are related to malignancy of astrocytomas. The higher the grade of tu- mor, the higher incidence rate of white matter disruption and interruption are (7.69%-72.73%). Conclusion: DTT plays an im- portant role in revealing the grade of brain astrocytomas.
出处
《中国临床医学影像杂志》
CAS
北大核心
2009年第4期240-242,254,共4页
Journal of China Clinic Medical Imaging
基金
江苏省卫生厅课题(H200729)。
关键词
脑肿瘤
星形细胞瘤
磁共振成像
Brain neoplasms
Astrocytoma
Magentic resonance imaging