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SpA致病性和基因表达调控的研究进展 被引量：3

The virulence and the gene regulatory mechanism of SpA
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摘要 SpA是金黄色葡萄球菌的重要毒力因子,在金葡菌抗吞噬、诱导B细胞凋亡、引起葡萄球菌性肺炎、心内膜炎等方面发挥重要作用。SpA的表达由非常精细复杂的系统调控。对SpA致病和基因调控机制的研究有助于发现治疗金葡菌感染的新途径。 SpA,one of the important virulence factors of Staphylococcus aureus,can impede phagocytosis,induce apoptosis of B cells,initiate staphylococcal pneumonia and endocarditis,et al.The expression of Spa gene is regulated by a very subtle and complicated systematic web.With the mechanism of the virulence and the gene regulation of Spa were known more and more clearly,New methods of the infection by Staphylococcus aureus were would be found.
作者 马立强 兰小鹏
机构地区 南京军区福州总医院解放军医学检验研究所
出处 《医学研究生学报》 CAS 2009年第4期427-430,I0002,共5页 Journal of Medical Postgraduates
基金 全军医学科学技术研究"十一五"计划资助项目(批准号:06G038)
关键词 金黄色葡萄球菌蛋白A 致病性 基因调控 Staphylococcus aureus Virulence Gene regulation
分类号 Q786 [生物学—分子生物学]
  • 相关文献

参考文献31

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共引文献3

同被引文献48

  • 1陈伶利,刘琳琳,曾力希,邓乐.金黄色葡萄球菌及SPA快速分离检验新技术的研究[J].中华微生物学和免疫学杂志,2004,24(9):754-754. 被引量：9
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引证文献3

二级引证文献22

医学研究生学报
2009年 第4期

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