降纤酶治疗急性脑梗死血液流变学观察

Investigate the effect of defibrase on hemorheology on the patients with acuteischemic stroke

目的：探讨降纤酶对急性脑梗死血液流变学的影响。方法：应用降纤酶治疗患者脑梗死118例，分别记录治疗前后血液流变学的变化。结果：用药后全血黏度、血浆黏度、红细胞聚集力、红细胞压积等均有不同程度下降。结论：降纤酶可降低血黏度、抑制红细胞聚集、改善微循环，有助于早期神经功能恢复。

Objective： To investigate the effect of defibrase on hemorheology on the patients with acute ischemic stroke.Methods：40 patients with acute ischemic stroke were treated by defibrase and the change of hemorheology was recorded before and after the treatment respectively, Results： The whole blood viscosity, the blood plasma viscosity, RBC aggregate index and RBC hematocrit got reduced on different degrees.Conclusion： Defibrase can reduce the blood viscosity, inhibit RBC aggregate, and improve the micro- circulation. It is helpful to recover the nerve function earlier.