痹祺胶囊联合泼尼松治疗风湿性多肌痛18例临床观察

Clinical observation about 18 cases of polymyalgia rheumatica by using Biqi capsule

目的:比较痹祺胶囊联合泼尼松与单纯使用泼尼松治疗风湿性多肌痛的疗效。方法:风湿性多肌痛患者39例,随机分为2组:治疗组18例,用痹祺胶囊和小剂量泼尼松治疗;对照组21例,小剂量泼尼松治疗,共治疗12周。观察肌肉疼痛、晨僵、T细胞亚群单抗(CD4、CD8)等指标,并对临床症状进行积分比较。结果:治疗组总有效率94.4%,对照组66.7%,治疗组改善风湿性多肌痛症状积分与对照组有显著差异。治疗组能够更好地调节风湿性多肌痛患者的免疫状态。结论:痹祺胶囊联合泼尼松有助于提高治疗风湿性多肌痛的疗效。

Objective：To compare the effect of curing polymyalgia rheumatica either by using both Biqi capsule and prednisone or by using prednisone alone. Methods： Thirty-nine patients of polymyalgia rheumatica were randomly divided into two groups, 18 patients in the treatment group treated with Biqi capsule and small dosage of prednisone; 21 patients in the control group treated with small dosage of prednisone. The therapeutic course was 12 weeks. The patients＇ symptoms of muscle ache, inflexibility in the morning and T-cell subsets determination （CD4, CD8）were observed and scores of clinical practice was made. Results： The respective total effective rate was 94.44% for the treatment group and 66.67% for the control group. There was distinctive difference in the scores for the treatment group and the control group in relieving the patients of the symptoms of polymyalgia rheumatica. The treatment group would help the patients of polymyalgia rheumatica to improve their immunity ability. Conclusion： The combination of Biqi capsule and prednisone can help to improve the effect of curing polymyalgia rheumatica.