慢性核黄疸所致脑性瘫痪的磁共振成像特征及临床意义

MRI Features in Children with Cerebral Palsy Induced by Chronic Kernicterus

目的探讨慢性期核黄疸所致脑性瘫痪的磁共振成像(MRI)特征。方法回顾性分析13例慢性核黄疸所致脑性瘫痪患儿的头颅MRI图像,并以同期6例年龄匹配的正常小儿头颅MRI作对照。该13例患儿临床诊断为不随意运动型(手足徐动型)脑性瘫痪。结果在MRI T2WI上,13例患儿双侧苍白球呈对称性高信号,在T1WI未见明显病变。结论双侧苍白球对称性T2WI高信号是慢性核黄疸引起脑性瘫痪的MRI特征性表现,有助于判断脑性瘫瘫的类型。

Objective To study the characteristic findings on magnetic resonance imaging （MRI） in children with cerebral palsy （CP） induced by chronic kernicterus. Methods The MR imagings in 13 CP cases induced by chronic kernicterus were retrospectively studied, which were compared with 6 healthy and age-matched controls. 13 cases were finally diagnosed as dyskinetie cerebral palsy （athetoid subtype）. Results In 13 cases, all showed symmetric high signals in the the globus pallidus on T2-weighted imaging. There were not apparent abnormality on T1-weighted imaging. Conclusion The bilateral high intensity signals in the globus pallidus on T2- weighted imaging are the characteristic findings on MRI in CP children induced by chronic kernicterus. Paying attention to the globus pallidus on MRI may be useful in determining the type of cerebral palsy.