转移因子联合半导体激光治疗复发性阿弗他溃疡的短期疗效观察

Short-term evaluation of the clinical efficacy of transfer factor in combination with semiconductor laser on recurrent aphthous ulcer

目的探讨转移因子(TF)口服治疗联合半导体激光治疗复发性阿弗他溃疡(RAU)的疗效及不良反应。方法将门诊100例RAU患者随机分为两组,治疗组60例,采用转移因子口服治疗联合半导体激光治疗;对照组40例,口服维生素C片剂和维生素B2,地塞米松粉剂涂搽溃疡处。两组分别观察1、2个疗程治疗结束后2周的临床疗效及不良反应。结果1个疗程治疗后2周治疗组的有效率(81.67%)高于对照组(55.0%)(P<0.05);2个疗程后2周治疗组有效率(86.67%)显著高于对照组(47.5%)(P<0.05)。两组比较差异均有统计学意义(均为P<0.05)。两组均未出现不良反应。结论应用转移因子口服治疗联合半导体激光治疗RAU有良好的短期治疗效果,无明显不良反应,能够明显的提高治疗RAU的有效率。

Objective To observe the short-term clinical efficacy of transfer factor （TF） in combination with semiconductor laser on recurrent aphthous ulcer （RAU）. Methods One hundred patients were randomly divided into the treatment group and the control group.The clinical effects analyzed statistically two weeks after the first and the second period of treatment. Results The effective rate of the treatment group （81.67%） was higher than that of the control group （55.5%） after the first period of treatment （P 〈 0.05）. The effective rate of the treatment group （86.67%） was significantly higher than that of the control group （47.5%） two weeks after the second period of the combination treatment （P 〈 0.05）. Conclcuions The combined treament of TF and semiconductor laser has a better short-term effect on RAU, with little toxicity and side effect, which significantly improves the effective rate on RAU.