钙吸收率分析方法研究

Research on Analysis Methods for Calcium Absorptivity

钙是人体内最重要的矿物元素,钙缺乏会导致多种疾病,选择有效补钙制剂是预防和治疗钙缺乏的重要手段。但是,市场上补钙制剂种类繁多,质量参差不齐,分析钙吸收率的方法显得尤为重要。本文对吸收率有关概念定义及吸收率和摄取量的关系作了介绍。提出确定钙的摄入量是分析钙吸收率的前提条件,摄入量过低或过高均不能对钙吸收作出客观的评价。分析了目前各钙剂评价方法优缺点并结合我们用Ca示踪法对钙吸收率分析方法研究作了系统的阐述。结论表明Ca分析钙吸收率方法是目前较科学有效的方法,该方法通过研究成熟后将会发展为分析钙吸收率的标准方法。

Calcium is the most important mineral element in the body and calcium deficiency can lead to various diseases. Supplementation of calcium is one of the important methods for the prevention and treatment of calcium deficien- cy. The types and quality of calcium supplements are great different in the market. Therefore, the analysis methods for calcium absorptivity seem particularly important. In this paper, the concept of the absorbability and the relationship be- tween calcium intake and absorbability were introduced. It was proposed that the precondition for successfully evaluating the effectiveness of calcium supplements is the determination of the calcium intake, the effectiveness of calcium supple- ments can not be objectively assessed when intake is too low or too high. Advantages and disadvantages of each analysis method for calcium absorptivity were analyzed and a new analysis method of labeling calcium pool by 41 Ca combine with our biological experiments was elucidated. The results show that the new analysis method of labeling calcium pool by 41^Ca is a more scientific and effective method and it would be a standard method to analyze the calcium absorptivity in the near future.