体外循环对婴幼儿免疫球蛋白的影响及临床补充人免疫球蛋白的方法

The impact of the cardiopulmonary bypass on the infant immunoglobulin and the method of the human immunoglobulin supplementary

目的探讨体外循环对婴幼儿免疫球蛋白的影响及临床补充人免疫球蛋白的方法。方法选取先天性心脏病婴幼儿30例，均分成三组，A、B二组为体外循环组，A组为术后补充人免疫球蛋白组，B组则不补充。C组为非体外循环对照组。三组病人均在术前、术后检测免疫球蛋白。结果体外循环可引起婴幼儿免疫球蛋白显著卡降，术后补充人免疫球蛋白可快速提升患儿免疫球蛋白水平。结论婴幼儿体外循环心脏术后可使免疫球蛋白下降1周，术后早期补充人免疫球蛋白能使患儿术后免疫球蛋白水平快速恢复正常，提高机体免疫力。

Objective To explore the effect of the cardiopulmonary bypass （CPB） on the intant immunoglobulin and the method.of the human immunoglobulin supplementary. Methods Thirty cases of infant congenital heart disease were mean divided into 3 groups （A, B and C）. Group A and B were the CPB cases, group C was comparison group. All the infants had been detected the blood immunoglobulin level before and after the cardiotic operation. Results The CPB can decline the infant blood immunoglobulin significantly and the supplementary of the human immunoglobulin after the operation can increase the infant blood immunoglobulin level rapidly. Conclusions The CPB operation can make the infant blood,immunoglobulin decline for a week and supply the human immunoglobulin early can make the infant blood immunoglobulin level restore normal rapidly and increase the body immunity.