摘要
目的:研究乙二胺四乙酸铁钠(NaFeEDTA)口服液治疗婴幼儿缺铁性贫血及对血铅水平的影响。方法:对101例缺铁性贫血(IDA)的患儿给予NaFeEDTA口服液,0.5mg·kg^(-1)·d^(-1),连服8周,治疗前后分别测定血常规和血铅,并与正常儿童对照。结果:用药8周后93.0%患儿血红蛋白(Hb)恢复至正常水平(P<0.01);治疗前IDA患儿血铅均较正常儿童高(P<0.05),治疗8周后血铅较治疗前明显降低(P<0.05)。结论:NaFeEDTA口服液治疗婴幼儿IDA临床效果好,可显著降低血铅水平。
Objective: To study the clinical efficacy and the influence on blood lead(Pb) of NaFeEDTA liquid for treatment of iron deficiency anemia(IDA) in children. Method: One hundred and one children with IDA were treated with NaFeEDTA liquid for 8 weeks,0.5mg·kg^-1·d^-1. The levels of blood routine and blood Pb were determined before and after treatment. They were also compared to the normal control. Result: The recovery rate of hemoglobin was 93% ( P 〈 0.01 ) after treatment. Before treatment the level of blood Pb was higher than those in the normal children (P 〈 0.05 ). The level of blood Pb was decreased significantly after treatment (P 〈 0.05). Conclusion: The effect of NaFeEDTA liquid is prominent to treat IDA in children. It can remarkably decrease the level of blood Pb.
出处
《中国药师》
CAS
2009年第5期562-563,共2页
China Pharmacist
基金
2005年河北省科学技术研究与发展第一批指导计划立项课题(编号05276413)