期刊文献+

反向遗传学在登革病毒研究中的应用

原文传递
导出
摘要 关于登革病毒及其感染的研究迄今还有很多尚未解决的问题,利用反向遗传学技术(reverse genetics approaches)对登革病毒进行研究是目前的热点。本文将就近年来反向遗传技术在登革病毒研究中的研究进展进行综述。
作者 韦艳 李德新
出处 《中华实验和临床病毒学杂志》 CAS CSCD 北大核心 2009年第2期F0003-F0004,共2页 Chinese Journal of Experimental and Clinical Virology
  • 相关文献

参考文献17

  • 1Cahour A, Pletnev A, Vazeille-Falcoz M, et al. Growth-Restricted Dengue Vires Mutants Containing Deletions in the 5' Noncoding Region of the RNA Genome. Virol, 1995, 207 : 68-76.
  • 2Men R, Bray M, Clark D, et al. Dengue Type 4 Virus Mutants Containing Deletions in the 39 Noncoding Region of the RNA Genome: Analysis of Growth Restriction in Cell Culture and Altered Viremia Pattern and Immunogenielty in Rhesus Monkeys. J Viral, 1996,70:3930-3937
  • 3Durbin AP, Karron RA, Sun W, et al. Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region. Am J Trop Med Hyg, 2001,65:405-413.
  • 4Guirakhoo F, Wehzin R, Chambers TJ, et al. Recombinant chimeric yellow fever-dengue type 2 virus is immunogenic and protective in nonhuman primates. J Virol, 2000,74 : 5477-5485.
  • 5Guirakhoo F, Arroyo J, Pugachev KV, et al. Construction, Safety, and Immunogenicity in Nonhuman Primates of a Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine. J Virol, 2001,75: 7290- 7304.
  • 6Guirakhoo F, Pugachev K, Zhang Z, et al. Safety and Efficacy of Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine Formulations in Nonhuman Primates. J Virol, 2004,78:4761-4775.
  • 7Bhamarapravati N, Sutee Y. Live attenuated tetravalent dengue vaccine. Vaccine, 2000, Suppl 2:44-47.
  • 8Huang CY, Butrapet S, Tsuchiya KR, et al. Dengue 2 PDK-53 virus as a chimeric carrier for tetravalent dengue vaccine development. J Virol, 2003,77 : 11436-11447.
  • 9Whitehead SS, Hanley KA, Blaney JE Jr, et al. Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice,and rhesus monkeys. Vaccine, 2003, 21:4307-4316.
  • 10Blaney JE, JR, Hanson CT, et al. Genetically modified, live attenuated dengue virus type 3 vaccine candidates. Am J Trop Med Hyg, 2004,71:811-821.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部