急性冠脉综合征患者血清CRP的变化及阿托伐他汀钙的影响
摘要
CRP是一种非特异性炎症标志物,是受IL-6等因子调控,由肝脏细胞合成的一种急性时相蛋白,对心血管有损害作用。正常情况下以微量形式存在于健康人血清中。当机体患有急性炎症性疾病、创伤、烧伤、器官移植等时,CRP水平升高。而许多研究资料已证明动脉硬化是一种慢性炎症性疾病,它是急性冠脉综合征(ACS)的发病基础。炎症反应可以促进动脉硬化(AS)的发展,
参考文献7
-
1Ridker PM,Rifai N,Rose L,et al.Compairson of C_reactive protei n an d low_density lipoprotein cholesterol levels in the prediction of first cardiova scular events.N Engl J Med,2002,347:1557.
-
2Verma S,Li SH,Badiwada MV,et al.Endothelin antagonism and interleukin_6 inhibition the proatherogenic effects of C_reactive protein.Circulation,2002,105:1890.
-
3Kohchik,Jakebayashis,Hirokit.Significance of adventitial inf-lammation of the coronary arteyy in patinets with unstable angina:results at autopsy.Circulation,2005,71:709.
-
4高润霖.他汀类药物在急性冠状动脉综合征的应用[J].中华心血管病杂志,2003,31(8):635-636. 被引量:150
-
5董宝林,赖泽仁.阿托伐他汀钙早期干预急性冠脉综合征患者效果评价[J].中国热带医学,2007,7(9):1588-1589. 被引量:3
-
6冯湘君,王品晓.阿托伐他汀对不稳定性心绞痛患者介入治疗后血清hs-CRP的影响[J].心脑血管病防治,2007,7(4):268-269. 被引量:6
-
7Nissen SE.High_dose statins in acute coronary syndromes:not just lipid le vels.JAMA,2004,292:365.
二级参考文献17
-
1Ridker PM,Rifai N,Rose L,et al.Compairson of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events[J].N Engl J Med,2002,347:1557.
-
2Verma S,Li SH,Badiwada MV,et al.Endothelin antagonism and interleukin-6 inhibition the proatherogenic effects of C-reactive protein[J].Circulation,2002,105:1890.
-
3Ruygrok PN,de Jaegeve PT,Van Dombury RT,et al.Clinical outcoml 10 years after attempted Percutaneous transluminal coronary angioplasty in 856 Patients[J].J AM coll cardiol,1996,27:1669-1677.
-
4Wilson SH,Berger PB,Mathew V,et al.Immediate and late outcomes after direct sternt implantation without tallon predilation[J].J Am coll Cardiol,2000,35:937-943.
-
5Ravkilde J,Nissen H,Mickley H,et al.Cardiac troponin T and CK-MB mass release after visually successful percutaneous transluminal coronary angioplasty in stable angina pectoris[J].Am Heart J,1994,127:13-20.
-
6Harrington RA.Cardiac enzyme elevation after percutaneous coronary intervention:myonecrosis the coronary microcirculation and mortalily[J].J Am coll Cardiol,2000,35:1142-1144.
-
7Serruys PW,De Feyter P,Macaya C,et al.Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention:a vandomized controlled trial[J].Jama,2002,287:3215-3222.
-
8Nissen SE.High-dose statins in acute coronary syndromes:not just lipid levels[J].JAMA,2004,292:365.
-
9Koukknnen H, Penttila K, Kemppainen A, et al. C-reactive protein, fibrinogen, interleukin-6 and tumor necrosis factor-alpha in the prognosic classi-fication of unstable engina pectors [J]. Ann Med, 2001, 33:37-47.
-
10Luo Y, Jiang D, Wen D, et al. Changes in serum interleukin-6 and high sensitivity C-reactive protein levels in patients with acute coronary syndrome and their responses to simvastatin [J] . Heart Vessels, 2004, 19 : 257-262.
共引文献153
-
1黄伟春,杨立华.辛伐他汀治疗急性心肌梗死合并房颤的疗效观察[J].广西医学院学报,2008,18(3):449-450. 被引量:2
-
2白红梅.阿托伐他汀治疗急性冠脉综合征临床观察[J].中国实用医药,2007,2(32):83-84. 被引量:1
-
3胡雪松,黄志超,许香广,张新霞,张国良.阿托伐他汀短期干预对急性冠脉综合征患者血浆OX40L及hsCRP的影响[J].岭南心血管病杂志,2009,15(5):366-369. 被引量:2
-
4董莉.辛伐他汀对急性冠脉综合征患者血管内皮功能的影响[J].中国乡村医药,2004,11(9):6-7.
-
5熊全庚,范木林,郭跃华.早期强化辛伐他汀治疗急性冠状动脉综合征的研究[J].临床心血管病杂志,2004,20(12):710-712. 被引量:25
-
6王海蓉,黄从新,江洪,李建军,李庚山.C反应蛋白直接刺激人单核细胞肿瘤坏死因子α与白细胞介素6的表达[J].中国动脉硬化杂志,2005,13(2):199-202. 被引量:5
-
7甘莉,凌燕君,朱丽萍.麝香保心丸治疗轻度高血压合并低密度脂蛋白胆固醇升高患者的体会[J].中成药,2005,27(5). 被引量:13
-
8潘长玲.阿托伐他汀对不稳定型心绞痛患者C-反应蛋白的影响[J].卫生职业教育,2005,23(12):106-107. 被引量:1
-
9冯姗,李颢.两种剂量辛伐他汀治疗急性冠脉综合征的临床疗效评价[J].中国医院用药评价与分析,2005,5(3):146-148. 被引量:2
-
10冯立刚.辛伐他汀对急性心肌梗死患者血脂水平和C反应蛋白的影响[J].中国卫生检验杂志,2005,15(10):1247-1247.
-
1刘桂芝.健康人Tp—e时间与Q—T间期比值的研究[J].心电学杂志,2010(5):401-403. 被引量:8
-
2翟航荣.老年糖尿病及低血糖反应16例分析[J].中国社区医师(医学专业),2011,13(9):54-54. 被引量:2
-
3周建立.胃石误诊误治浅析[J].河南外科学杂志,2002,8(5):78-79. 被引量:1
-
4米本义.胃食管反流病误诊为心绞痛11例分析[J].实用心脑肺血管病杂志,2008,16(10):48-48.
-
5吕丹,王树厚.急性主动脉夹层30例临床分析[J].临床军医杂志,2013,41(2):196-197.
-
6马志丽,郑秀玲,王琴姚,利蕊.原发性肝癌并发上消化道出血的观察与护理[J].齐齐哈尔医学院学报,2005,26(1):100-100.
-
7朱海燕.胃食管反流病误诊为心绞痛18例分析[J].中国医学创新,2009,6(12):87-87.
-
8胡琛.内皮素与心血管病学的联系[J].国外医学(老年医学分册),1995,16(6):256-258. 被引量:14
-
9高宇,折瑞莲,黎燕.饮食和运动干预对妊娠期糖尿病患者血浆脂肪因子调控的实验研究[J].中国实验诊断学,2014,18(4):598-600. 被引量:16
-
10侯卫丽.奥曲肽联合乌司他丁治疗急性重症胰腺炎临床疗效分析[J].现代诊断与治疗,2016,27(3):462-463. 被引量:5